Transformation of the Davenport Diagram to a Computerized Artificial Neural Network
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Author(s)
Abstract
The Davenport diagram, which illustrates the interactions of pH, bicarbonate and pCO2 as related to respiratory/metabolic phases of acidosis/alkalosis was transformed into a computerized neural network. This transformation enables computer-assisted prediction of acidosis/alkalosis subtypes on the basis of any two factors from pH, bicarbonate and pCO2. Furthermore, this neural network can eventually be trained to predict changes in acid-base balance on the basis of additional factors; illustrating the utility of neural network analysis as a dynamic predictive tool in healthcare.
Keywords
Davenport diagram, neural network, nomogram, acidosis, alkalosis
Cite this paper
Timothy J Smith, RPh, PhD,
Transformation of the Davenport Diagram to a Computerized Artificial Neural Network
, SCIREA Journal of Medicine.
Volume 2, Issue 1, February 2018 | PP. 1-7.
References
[ 1 ] | Padar, S. and Smith, TJ. Transformation of an acetaminophen toxicity nomogram to an artificial neural network. International Journal of Clinical Pharmacology and Therapeutics 1999;37:446-448. https://www.ncbi.nlm.nih.gov/pubmed/?term=int+J+Clin+Pharmacol+Ther+37%3A446-448+1999+ |
[ 2 ] | Smith, TJ. Transformation of a Nomogram for Drug-induced QT-Prolongation to a Computerized Neural Network, SCIREA Journal of Pharmacy. 2017;2(1):1 - 6.http://www.scirea.org/journal/PaperInformation?PaperID=299 |
[ 3 ] | Davenport, HW. The ABC of Acid-Base Chemistry: The Elements of Physiological Blood-Gas Chemistry for Medical Students and Physicians (Sixth ed.). Chicago: The University of Chicago Press. 1974.http://press.uchicago.edu/ucp/books/book/chicago/A/bo3622345.html |
[ 4 ] | Acid-base nomogram, Wikipedia; November 9, 2017.https://en.wikipedia.org/wiki/Acid%E2%80%93base_homeostasis#/media/File:Acid-base_nomogram.svg |
[ 5 ] | Hamm, LL, Nakhoul, N and Hering-Smith, KS. Acid-Base Homeostasis. Clin J Am Soc Nephrol. 2015;10(12): 2232–2242. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670772/ |
[ 6 ] | Kitterer D1, Schwab M, Alscher MD, Braun N, Latus J. Drug-induced acid-base disorders. Pediatr Nephrol. 2015;30(9):1407-23.https://www.ncbi.nlm.nih.gov/pubmed/25370778 |