Synthesis of process related Dapsone impurities : Selective diazotization of aromatic di-amine
DOI: 10.54647/chemistry15253 92 Downloads 160573 Views
Author(s)
Abstract
Process related two impurities of Dapsone were synthesized by applying cu-catalyzed conversions for the impurity profile and toxicological study. Controlled mono-diazotization of Dapsone followed by insitu iodination is the key step of our synthesis.
Keywords
Non-aqueous diazotization, Ullmann reactions, Process related impurities, Impurity Profile, Isoamyl nitrite and Hydroxylation.
Cite this paper
Mahesh Bandishti, Balaji Chaugule, Chinmoy Pramanik, Ganesh Karhade, Ashok Chaudhari,
Synthesis of process related Dapsone impurities : Selective diazotization of aromatic di-amine
, SCIREA Journal of Chemistry.
Volume 7, Issue 2, April 2022 | PP. 33-41.
10.54647/chemistry15253
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